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Conference Abstract: DIILD Animal Models
Systematic review: In vivo imaging in animal models relevant to drug-induced Interstitial lung disease (DIILD)
Irma Mahmutovic Persson, Karin von Wachenfeldt, Kashmira Pindoria, Michael Haase, Simon Campbell, Juan X. Delgado, Mark Wright, John C. Waterton and Lars E. Olsson - on behalf of the TRISTAN Consortium
European Respiratory Society, International Congress 2018, 15-19 September 2018, Paris, France
Translational Imaging Biomarkers (IB) are needed to avoid or manage drug-toxicity, resulting in drug-induced interstitial lung disease (DIILD). We reviewed the literature on in vivo imaging to detect and assess lung lesions in animal models with relevance to DIILD and with pathological changes resembling clinical DIILD.